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Progression of Epididymal Maldevelopment Into Hamartoma-like Neoplasia in VHL Disease

Inactivation of the von Hippel-Lindau (VHL) gene and activation of the hypoxia-inducible factor (HIF) in susceptible cells precedes formation of tumorlets and frank tumor in the epididymis of male VHL patients. We performed detailed histologic and molecular pathologic analysis of tumor-free epididym...

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Autores principales: Mehta, Gautam U, Shively, Sharon B, Duong, Heng, Tran, Maxine GB, Moncrief, Travis J, Smith, Jonathan H, Li, Jie, Edwards, Nancy A, Lonser, Russell R, Zhuang, Zhengping, Merrill, Marsha J, Raffeld, Mark, Maxwell, Patrick H, Oldfield, Edward H, Vortmeyer, Alexander O
Formato: Artigo
Lenguaje:Inglês
Publicado: Neoplasia Press Inc. 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546591/
https://ncbi.nlm.nih.gov/pubmed/18813354
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