Progression of Epididymal Maldevelopment Into Hamartoma-like Neoplasia in VHL Disease

Inactivation of the von Hippel-Lindau (VHL) gene and activation of the hypoxia-inducible factor (HIF) in susceptible cells precedes formation of tumorlets and frank tumor in the epididymis of male VHL patients. We performed detailed histologic and molecular pathologic analysis of tumor-free epididym...

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Hauptverfasser: Mehta, Gautam U, Shively, Sharon B, Duong, Heng, Tran, Maxine GB, Moncrief, Travis J, Smith, Jonathan H, Li, Jie, Edwards, Nancy A, Lonser, Russell R, Zhuang, Zhengping, Merrill, Marsha J, Raffeld, Mark, Maxwell, Patrick H, Oldfield, Edward H, Vortmeyer, Alexander O
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press Inc. 2008
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546591/
https://ncbi.nlm.nih.gov/pubmed/18813354
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