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Pin1-dependent Prolyl Isomerization Modulates the Stress-induced Phosphorylation of High Molecular Weight Neurofilament Protein

Aberrant phosphorylation of neuronal cytoskeletal proteins is a key pathological event in neurodegenerative disorders such as Alzheimer disease (AD) and amyotrophic lateral sclerosis, but the underlying mechanisms are still unclear. Previous studies have shown that Pin1, a peptidylprolyl cis/trans-i...

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Autori principali: Rudrabhatla, Parvathi, Zheng, Ya-Li, Amin, Niranjana D., Kesavapany, Sashi, Albers, Wayne, Pant, Harish C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546547/
https://ncbi.nlm.nih.gov/pubmed/18635547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801633200
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