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Peptidyl-Prolyl Isomerase 1 Regulates Protein Phosphatase 2A-Mediated Topographic Phosphorylation of Neurofilament Proteins

In normal neurons, neurofilament (NF) proteins are phosphorylated in the axonal compartment. However, in neurodegenerative disorders such as Alzheimer's disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS), NF proteins are aberrantly hyperphosphorylated within th...

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Hlavní autoři: Rudrabhatla, Parvathi, Albers, Wayne, Pant, Harish C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849796/
https://ncbi.nlm.nih.gov/pubmed/19940183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4469-09.2009
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