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Peptidyl-Prolyl Isomerase 1 Regulates Protein Phosphatase 2A-Mediated Topographic Phosphorylation of Neurofilament Proteins

In normal neurons, neurofilament (NF) proteins are phosphorylated in the axonal compartment. However, in neurodegenerative disorders such as Alzheimer's disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS), NF proteins are aberrantly hyperphosphorylated within th...

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Detalhes bibliográficos
Main Authors: Rudrabhatla, Parvathi, Albers, Wayne, Pant, Harish C.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849796/
https://ncbi.nlm.nih.gov/pubmed/19940183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4469-09.2009
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