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Peptidyl-Prolyl Isomerase 1 Regulates Protein Phosphatase 2A-Mediated Topographic Phosphorylation of Neurofilament Proteins

In normal neurons, neurofilament (NF) proteins are phosphorylated in the axonal compartment. However, in neurodegenerative disorders such as Alzheimer's disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS), NF proteins are aberrantly hyperphosphorylated within th...

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Autors principals: Rudrabhatla, Parvathi, Albers, Wayne, Pant, Harish C.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849796/
https://ncbi.nlm.nih.gov/pubmed/19940183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4469-09.2009
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