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TGF-β and IL-6 signals modulate chromatin binding and promoter occupancy by acetylated FOXP3
Expression of FOXP3, a potent gene-specific transcriptional repressor, in regulatory T cells is required to suppress autoreactive and alloreactive effector T cell function. Recent studies have shown that FOXP3 is an acetylated protein in a large nuclear complex and FOXP3 actively represses transcrip...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2544572/ https://ncbi.nlm.nih.gov/pubmed/18779564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806726105 |
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