1,3-Disubstituted Ureas Functionalized with Ether Groups are Potent Inhibitors of the Soluble Epoxide Hydrolase with Improved Pharmacokinetic Properties

Lignende værker

• Salicylate-urea based soluble epoxide hydrolase inhibitors with high metabolic and chemical stabilities
  af: Kasagami, Takeo, et al.
  Udgivet: (2009)
• Biologically Active Ester Derivatives as Potent Inhibitors of the Soluble Epoxide Hydrolase
  af: Kim, In-Hae, et al.
  Udgivet: (2012)
• Pharmacokinetic Screening of Soluble Epoxide Hydrolase Inhibitors in Dogs
  af: Tsai, Hsing-Ju, et al.
  Udgivet: (2010)
• Potent urea and carbamate inhibitors of soluble epoxide hydrolases
  af: Morisseau, Christophe, et al.
  Udgivet: (1999)
• Incorporation of piperazino functionality into 1,3-disubstituted urea as the tertiary pharmacophore affording potent inhibitors of soluble epoxide hydrolase with improved pharmacokinetic properties
  af: Huang, Shao-Xu, et al.
  Udgivet: (2010)