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Var2CSA DBL6-epsilon domain expressed in HEK293 induces limited cross-reactive and blocking antibodies to CSA binding parasites

BACKGROUND: Pregnancy-associated malaria (PAM) is a serious consequence of Plasmodium falciparum-infected erythrocytes sequestration in the placenta through the adhesion to the placental receptor chondroitin sulfate A (CSA). Although women become resistant to PAM as they acquire transcending inhibit...

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Detalhes bibliográficos
Main Authors: Fernandez, Pablo, KViebig, Nicola, Dechavanne, Sébastien, Lépolard, Catherine, Gysin, Jürg, Scherf, Artur, Gamain, Benoit
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2543044/
https://ncbi.nlm.nih.gov/pubmed/18771584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-7-170
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