Structure of the DBL3X-DBL4ε region of the VAR2CSA placental malaria vaccine candidate: insight into DBL domain interactions

The human malaria parasite, Plasmodium falciparum, is able to evade spleen-mediated clearing from blood stream by sequestering in peripheral organs. This is due to the adhesive properties conferred by the P. falciparum Erythrocyte Membrane Protein 1 (PfEMP1) family exported by the parasite to the su...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Gangnard, Stéphane, Lewit-Bentley, Anita, Dechavanne, Sébastien, Srivastava, Anand, Amirat, Faroudja, Bentley, Graham A., Gamain, Benoît
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4598876/
https://ncbi.nlm.nih.gov/pubmed/26450557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14868
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