Down-selection of the VAR2CSA DBL1-2 expressed in E. coli as a lead antigen for placental malaria vaccine development

Over 50 million women are exposed to the risk of malaria during pregnancy every year. Malaria during pregnancy is a leading global cause of maternal morbidity and adverse pregnancy outcomes. Adhesion of Plasmodium falciparum-infected erythrocytes to placental chondroitin-4-sulfate (CSA) has been lin...

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Bibliographic Details
Published in:NPJ Vaccines
Main Authors: Chêne, Arnaud, Gangnard, Stéphane, Dechavanne, Célia, Dechavanne, Sebastien, Srivastava, Anand, Tétard, Marilou, Hundt, Sophia, Leroy, Odile, Havelange, Nicolas, Viebig, Nicola K., Gamain, Benoît
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6050242/
https://ncbi.nlm.nih.gov/pubmed/30038803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-018-0064-6
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