VAR2CSA binding phenotype has ancient origin and arose before Plasmodium falciparum crossed to humans: implications in placental malaria vaccine design

VAR2CSA is a leading candidate for developing a placental malaria (PM) vaccine that would protect pregnant women living in malaria endemic areas against placental infections and improve birth outcomes. Two VAR2CSA-based PM vaccines are currently under clinical trials, but it is still unclear if the...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gangnard, Stéphane, Chêne, Arnaud, Dechavanne, Sébastien, Srivastava, Anand, Avril, Marion, Smith, Joseph D., Gamain, Benoît
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6861233/
https://ncbi.nlm.nih.gov/pubmed/31740695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53334-8
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