Strain-Transcendent Immune Response to Recombinant Var2CSA DBL5-ε Domain Block P. falciparum Adhesion to Placenta-Derived BeWo Cells under Flow Conditions

BACKGROUND: Pregnancy-associated malaria (PAM) is a serious consequence of the adhesion to the placental receptor chondroitin sulfate A (CSA) of Plasmodium falciparum-infected erythrocytes (PE) expressing the large cysteine-rich multi-domain protein var2CSA. Women become resistant to PAM, and develo...

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Detalhes bibliográficos
Main Authors: Fernandez, Pablo, Petres, Stéphane, Mécheri, Salaheddine, Gysin, Jürg, Scherf, Artur
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933227/
https://ncbi.nlm.nih.gov/pubmed/20838433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012558
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