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Characterization of VAR2CSA-deficient Plasmodium falciparum-infected erythrocytes selected for adhesion to the BeWo placental cell line

BACKGROUND: Malaria in pregnancy is characterized by accumulation of infected erythrocytes (IE) in the placenta. The key ligand identified as mediating this process is a Plasmodium falciparum erythrocyte membrane protein 1 family member, termed VAR2CSA. VAR2CSA appears to be the main ligand responsi...

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Autores principales: Yosaatmadja, Francisca, Andrews, Katherine T, Duffy, Michael F, Brown, Graham V, Beeson, James G, Rogerson, Stephen J
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329659/
https://ncbi.nlm.nih.gov/pubmed/18364051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-7-51
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