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Structural basis for placental malaria mediated by Plasmodium falciparum VAR2CSA
Plasmodium falciparum VAR2CSA binds to chondroitin sulfate A (CSA) on the surface of the syncytiotrophoblast during placental malaria. This interaction facilitates placental sequestration of malaria parasites resulting in severe health outcomes for both the mother and her offspring. Furthermore, CSA...
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| 發表在: | Nat Microbiol |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7914210/ https://ncbi.nlm.nih.gov/pubmed/33452495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-020-00858-9 |
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