Cross-Reactive Surface Epitopes on Chondroitin Sulfate A-Adherent Plasmodium falciparum-Infected Erythrocytes Are Associated with Transcription of var2csa

Malaria in pregnancy is associated with placental accumulation of Plasmodium falciparum-infected erythrocytes (IE) that adhere to chondroitin sulfate A (CSA). Adhesion is mediated by P. falciparum erythrocyte membrane protein 1 (PfEMP1), a variant parasite protein expressed on the surface of IE and...

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Main Authors: Elliott, Salenna R., Duffy, Michael F., Byrne, Timothy J., Beeson, James G., Mann, Emily J., Wilson, Danny W., Rogerson, Stephen J., Brown, Graham V.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Fungal and Parasitic Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087379/
https://ncbi.nlm.nih.gov/pubmed/15845490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.5.2848-2856.2005
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