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Mutants defective in herpes simplex virus type 2 ICP4: isolation and preliminary characterization.

Vero cells were biochemically transformed with the gene encoding ICP4 of herpes simplex virus type 2 (HSV-2). These cells were used as permissive hosts to isolate and propagate HSV-2 mutants defective in this gene. Two mutants, designated hr259 and hr79, were isolated. Neither mutant grew in nontran...

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Bibliographic Details
Published in:J Virol
Main Authors: Smith, C A, Schaffer, P A
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1987
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254068/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3029403/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.61.4.1092-1097.1987
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