Deletion mutants in the gene encoding the herpes simplex virus type 1 immediate-early protein ICP0 exhibit impaired growth in cell culture.

We report the construction and characterization of deletion mutants in the herpes simplex virus type 1 gene encoding the immediate-early protein ICP0. In the event that ICP0 proved to play an essential role in virus replication, ICP0-transformed Vero cells were generated to serve as permissive hosts...

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Main Authors: Sacks, W R, Schaffer, P A
Formato: Artigo
Idioma:Inglês
Publicado: 1987
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC254026/
https://ncbi.nlm.nih.gov/pubmed/3027408
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