Prolonged gene expression and cell survival after infection by a herpes simplex virus mutant defective in the immediate-early genes encoding ICP4, ICP27, and ICP22.

Míreanna Comhchosúla

• Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4.
  le: DeLuca, N A, et al.
  Foilsithe: (1985)
• Overexpression of the herpes simplex virus type 1 immediate-early regulatory protein, ICP27, is responsible for the aberrant localization of ICP0 and mutant forms of ICP4 in ICP4 mutant virus-infected cells.
  le: Zhu, Z, et al.
  Foilsithe: (1996)
• Temperature-sensitive mutants in herpes simplex virus type 1 ICP4 permissive for early gene expression.
  le: DeLuca, N A, et al.
  Foilsithe: (1984)
• The herpes simplex virus immediate-early protein ICP0 affects transcription from the viral genome and infected-cell survival in the absence of ICP4 and ICP27.
  le: Samaniego, L A, et al.
  Foilsithe: (1997)
• Functional interactions between herpes simplex virus immediate-early proteins during infection: gene expression as a consequence of ICP27 and different domains of ICP4.
  le: Samaniego, L A, et al.
  Foilsithe: (1995)