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Deletion mutants in the gene encoding the herpes simplex virus type 1 immediate-early protein ICP0 exhibit impaired growth in cell culture.

We report the construction and characterization of deletion mutants in the herpes simplex virus type 1 gene encoding the immediate-early protein ICP0. In the event that ICP0 proved to play an essential role in virus replication, ICP0-transformed Vero cells were generated to serve as permissive hosts...

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Vydáno v:J Virol
Hlavní autoři: Sacks, W R, Schaffer, P A
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1987
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254026/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3027408/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.61.3.829-839.1987
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