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Overexpression of the herpes simplex virus type 1 immediate-early regulatory protein, ICP27, is responsible for the aberrant localization of ICP0 and mutant forms of ICP4 in ICP4 mutant virus-infected cells.

ICP0 and ICP4 are immediate-early regulatory proteins of herpes simplex virus type 1. Previous studies by Knipe and Smith demonstrated that these two proteins are characteristically observed in the nuclei of wild-type virus-infected cells but predominantly in the cytoplasms of cells infected with se...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhu, Z, DeLuca, N A, Schaffer, P A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1996
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC190492/
https://ncbi.nlm.nih.gov/pubmed/8764045
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