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Overexpression of the herpes simplex virus type 1 immediate-early regulatory protein, ICP27, is responsible for the aberrant localization of ICP0 and mutant forms of ICP4 in ICP4 mutant virus-infected cells.

ICP0 and ICP4 are immediate-early regulatory proteins of herpes simplex virus type 1. Previous studies by Knipe and Smith demonstrated that these two proteins are characteristically observed in the nuclei of wild-type virus-infected cells but predominantly in the cytoplasms of cells infected with se...

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Bibliografske podrobnosti
izdano v:J Virol
Principais autores: Zhu, Z, DeLuca, N A, Schaffer, P A
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1996
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC190492/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8764045/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.70.8.5346-5356.1996
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