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Structural identification of the pathway of long-range communication in an allosteric enzyme

Allostery is a common mechanism of regulation of enzyme activity and specificity, and its signatures are readily identified from functional studies. For many allosteric systems, structural evidence exists of long-range communication among protein domains, but rarely has this communication been trace...

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Bibliografiske detaljer
Main Authors: Gandhi, Prafull S., Chen, Zhiwei, Mathews, F. Scott, Di Cera, Enrico
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538848/
https://ncbi.nlm.nih.gov/pubmed/18250335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710894105
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