Distinct Effects of IL-18 on the Engraftment and Function of Human Effector CD8(+) T Cells and Regulatory T Cells

IL-18 has pleotropic effects on the activation of T cells during antigen presentation. We investigated the effects of human IL-18 on the engraftment and function of human T cell subsets in xenograft mouse models. IL-18 enhanced the engraftment of human CD8(+) effector T cells and promoted the develo...

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Main Authors: Carroll, Richard G., Carpenito, Carmine, Shan, Xiaochuan, Danet-Desnoyers, Gwenn, Liu, Ronghua, Jiang, Shuguang, Albelda, Steven M., Golovina, Tatiana, Coukos, George, Riley, James L., Jonak, Zdenka L., June, Carl H.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2008
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538560/
https://ncbi.nlm.nih.gov/pubmed/18818761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003289
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