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Renal Na(+)-K(+)-Cl(−) cotransporter activity and vasopressin-induced trafficking are lipid raft-dependent

Apical bumetanide-sensitive Na(+)-K(+)-2Cl(−) cotransporter (NKCC2), the kidney-specific member of a cation-chloride cotransporter superfamily, is an integral membrane protein responsible for the transepithelial reabsorption of NaCl. The role of NKCC2 is essential for renal volume regulation. Vasopr...

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Detalhes bibliográficos
Main Authors: Welker, Pia, Böhlick, Alexandra, Mutig, Kerim, Salanova, Michele, Kahl, Thomas, Schlüter, Hartmut, Blottner, Dieter, Ponce-Coria, Jose, Gamba, Gerardo, Bachmann, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536870/
https://ncbi.nlm.nih.gov/pubmed/18579701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90227.2008
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