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Measurement of pulsatile insulin secretion in the rat: direct sampling from the hepatic portal vein

It has previously been shown that insulin is secreted in discrete secretory bursts by sampling directly from the portal vein in the dog and humans. Deficient pulsatile insulin secretion is the basis for impaired insulin secretion in type 2 diabetes. However, while novel genetically modified disease...

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Bibliografische gegevens
Hoofdauteurs: Matveyenko, Aleksey V., Veldhuis, Johannes D., Butler, Peter C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536733/
https://ncbi.nlm.nih.gov/pubmed/18577690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.90335.2008
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