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Fatty acids in the portal vein of the rat regulate hepatic insulin clearance.

The effects of FFA on hepatic insulin clearance were studied in the in situ perfused rat liver. Clearance decreased with increasing body weight (age) of the rats. When FFA were added to the perfusate a 40% reduction of hepatic removal of insulin was found over the normal, physiological range (less t...

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Pubblicato in:J Clin Invest
Autori principali: Svedberg, J, Strömblad, G, Wirth, A, Smith, U, Björntorp, P
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1991
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295800/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1752963/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115534
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