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Measurement of pulsatile insulin secretion in the rat: direct sampling from the hepatic portal vein

It has previously been shown that insulin is secreted in discrete secretory bursts by sampling directly from the portal vein in the dog and humans. Deficient pulsatile insulin secretion is the basis for impaired insulin secretion in type 2 diabetes. However, while novel genetically modified disease...

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Autori principali: Matveyenko, Aleksey V., Veldhuis, Johannes D., Butler, Peter C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536733/
https://ncbi.nlm.nih.gov/pubmed/18577690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.90335.2008
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