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Adaptations in pulsatile insulin secretion, hepatic insulin clearance, and β-cell mass to age-related insulin resistance in rats

In health insulin is secreted in discrete insulin secretory bursts from pancreatic β-cells, collectively referred to as β-cell mass. We sought to establish the relationship between β-cell mass, insulin secretory-burst mass, and hepatic insulin clearance over a range of age-related insulin sensitivit...

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Bibliografiska uppgifter
Huvudupphovsmän: Matveyenko, Aleksey V., Veldhuis, Johannes D., Butler, Peter C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2008
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575907/
https://ncbi.nlm.nih.gov/pubmed/18664594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.90451.2008
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