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Investigation of Mcp1 as a Quantitative Trait Gene for Prion Disease Incubation Time in Mouse

The genetic basis of prion disease incubation time is principally determined by polymorphisms in the prion protein gene, Prnp. However, it is now known that other genetic factors are important. Several quantitative trait loci (QTL) have been identified across the genome including a broad region of l...

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Détails bibliographiques
Auteurs principaux: O'Shea, Marie, Maytham, Emma G., Linehan, Jackie M., Brandner, Sebastian, Collinge, John, Lloyd, Sarah E.
Format: Artigo
Langue:Inglês
Publié: Genetics Society of America 2008
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2535705/
https://ncbi.nlm.nih.gov/pubmed/18716327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.090894
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