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Investigation of Mcp1 as a Quantitative Trait Gene for Prion Disease Incubation Time in Mouse

The genetic basis of prion disease incubation time is principally determined by polymorphisms in the prion protein gene, Prnp. However, it is now known that other genetic factors are important. Several quantitative trait loci (QTL) have been identified across the genome including a broad region of l...

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Detalhes bibliográficos
Main Authors: O'Shea, Marie, Maytham, Emma G., Linehan, Jackie M., Brandner, Sebastian, Collinge, John, Lloyd, Sarah E.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2535705/
https://ncbi.nlm.nih.gov/pubmed/18716327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.090894
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