Loading...

Rapid-reaction Kinetic Characterization of the Pathway of Streptokinase-Plasmin Catalytic Complex Formation

Binding of the fibrinolytic proteinase plasmin (Pm) to streptokinase (SK) in a tight stoichiometric complex transforms Pm into a potent proteolytic activator of plasminogen. SK binding to the catalytic domain of Pm, with a dissociation constant of 12 pm, is assisted by SK Lys(414) binding to a Pm kr...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Verhamme, Ingrid M., Bock, Paul E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533780/
https://ncbi.nlm.nih.gov/pubmed/18658146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804038200
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!