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Identification of a New Exosite Involved in Catalytic Turnover by the Streptokinase-Plasmin Activator Complex during Human Plasminogen Activation

With the goal of identifying hitherto unknown surface exosites of streptokinase involved in substrate human plasminogen recognition and catalytic turnover, synthetic peptides encompassing the 170 loop (CQFTPLNPDDDFRPGLKDTKLLC) in the β-domain were tested for selective inhibition of substrate human p...

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Detalhes bibliográficos
Main Authors: Aneja, Rachna, Datt, Manish, Singh, Balwinder, Kumar, Shekhar, Sahni, Girish
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781679/
https://ncbi.nlm.nih.gov/pubmed/19801674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.046573
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