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Role of the Streptokinase α-Domain in the Interactions of Streptokinase with Plasminogen and Plasmin

The role of the streptokinase (SK) α-domain in plasminogen (Pg) and plasmin (Pm) interactions was investigated in quantitative binding studies employing active site fluorescein-labeled [Glu]Pg, [Lys]Pg, and [Lys]Pm, and the SK truncation mutants, SK-(55–414), SK-(70–414), and SK-(152–414). Lysine bi...

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Autori principali: Bean, Ronald R., Verhamme, Ingrid M., Bock, Paul E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292463/
https://ncbi.nlm.nih.gov/pubmed/15623524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M411637200
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