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Streptavidin in Antibody Pretargeting. 5. Chemical Modification of Recombinant Streptavidin for Labeling with the α-Particle Emitting Radionuclides (213)Bi and (211)At

We are investigating the use of recombinant streptavidin (rSAv) as a carrier molecule for the short-lived α-particle emitting radionuclides (213)Bi (t(1/2) = 45.6 min) and (211)At (t(1/2) = 7.21 h) in cancer therapy. To utilize rSAv as a carrier, it must be modified in a manner that permits rapid ch...

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Bibliografische gegevens
Hoofdauteurs: Wilbur, D. Scott, Hamlin, Donald K., Chyan, Ming-Kuan, Brechbiel, Martin W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533765/
https://ncbi.nlm.nih.gov/pubmed/18072725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc7002428
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