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Reagents for Astatination of Biomolecules. 3. Comparison of closo-Decaborate(2-) and closo-Dodecaborate(2-) Moieties as Reactive Groups for Labeling with Astatine-211

In vivo deastatination has been a major problem in the development of reagents for therapeutic applications of the α-particle emitting radionuclide (211)At. Our prior studies demonstrated that the use of a closo-decaborate(2-) ([closo-B(10)H(9)R](2−)) moiety for (211)At labeling of biomolecules prov...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Wilbur, D. Scott, Chyan, Ming-Kuan, Hamlin, Donald K., Perry, Matthew A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668518/
https://ncbi.nlm.nih.gov/pubmed/19236022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc800515d
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