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Effect of roflumilast on inflammatory cells in the lungs of cigarette smoke-exposed mice
BACKGROUND: We reported that roflumilast, a phosphodiesterase 4 inhibitor, given orally at 5 mg/kg to mice prevented the development of emphysema in a chronic model of cigarette smoke exposure, while at 1 mg/kg was ineffective. Here we investigated the effects of roflumilast on the volume density (V...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2533284/ https://ncbi.nlm.nih.gov/pubmed/18755021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2466-8-17 |
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