Functional contribution of sphingosine‐1‐phosphate to airway pathology in cigarette smoke‐exposed mice

BACKGROUND AND PURPOSE: A critical role for sphingosine kinase/sphingosine‐1‐phosphate (S1P) pathway in the control of airway function has been demonstrated in respiratory diseases. Here, we address S1P contribution in a mouse model of mild chronic obstructive pulmonary disease (COPD). EXPERIMENTAL...

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Vydáno v:Br J Pharmacol
Hlavní autoři: De Cunto, Giovanna, Brancaleone, Vincenzo, Riemma, Maria Antonietta, Cerqua, Ida, Vellecco, Valentina, Spaziano, Giuseppe, Cavarra, Eleonora, Bartalesi, Barbara, D'Agostino, Bruno, Lungarella, Giuseppe, Cirino, Giuseppe, Lucattelli, Monica, Roviezzo, Fiorentina
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989954/
https://ncbi.nlm.nih.gov/pubmed/31499592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14861
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