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Effect of roflumilast on inflammatory cells in the lungs of cigarette smoke-exposed mice
<p>Abstract</p> <p>Background</p> <p>We reported that roflumilast, a phosphodiesterase 4 inhibitor, given orally at 5 mg/kg to mice prevented the development of emphysema in a chronic model of cigarette smoke exposure, while at 1 mg/kg was ineffective. Here we investiga...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2008-08-01
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| Colecção: | BMC Pulmonary Medicine |
| Acesso em linha: | http://www.biomedcentral.com/1471-2466/8/17 |
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