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Is neutrophil elastase the missing link between emphysema and fibrosis? Evidence from two mouse models

BACKGROUND: The separation of emphysema from fibrosis is not as clear-cut as it was thought in early studies. These two pathologies may be present at the same time in human lungs and in mice either instilled with elastolytic enzymes or bleomycin or exposed to cigarette-smoke. According to a current...

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Bibliographic Details
Main Authors: Lucattelli, Monica, Bartalesi, Barbara, Cavarra, Eleonora, Fineschi, Silvia, Lunghi, Benedetta, Martorana, Piero A, Lungarella, Giuseppe
Format: Artigo
Language:Inglês
Published: BioMed Central 2005
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1184102/
https://ncbi.nlm.nih.gov/pubmed/16045796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-6-83
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