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Microsecond acquisition of heterogeneous structure in the folding of a TIM barrel protein
The earliest kinetic folding events for (βα)(8) barrels reflect the appearance of off-pathway intermediates. Continuous-flow microchannel mixing methods interfaced to small-angle x-ray scattering (SAXS), circular dichroism (CD), time-resolved Förster resonant energy transfer (trFRET), and time-resol...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2533196/ https://ncbi.nlm.nih.gov/pubmed/18757725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802788105 |
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