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NMR Analysis of Partially-Folded States and Persistent Structure in the Alpha Subunit of Tryptophan Synthase: Implications for the Equilibrium Folding Mechanism of a 29 kDa TIM Barrel Protein

Structural insights into the equilibrium folding mechanism of the alpha subunit of tryptophan synthase (αTS) from E. coli, a (βα)(8) TIM barrel protein, were obtained with a pair of complementary NMR spectroscopic techniques. The secondary structures of rare high-energy partially-folded states were...

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Detalhes bibliográficos
Main Authors: Vadrevu, Ramakrishna, Wu, Ying, Matthews, C. Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2310134/
https://ncbi.nlm.nih.gov/pubmed/18234216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.11.010
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