טוען...
Oncogenic Kit controls neoplastic mast cell growth through a Stat5/PI3-kinase signaling cascade
The D816V-mutated variant of Kit triggers multiple signaling pathways and is considered essential for malignant transformation in mast cell (MC) neoplasms. We here describe that constitutive activation of the Stat5-PI3K-Akt-cascade controls neoplastic MC development. Retrovirally transduced active S...
שמור ב:
| Main Authors: | , , , , , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society of Hematology
2008
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2532813/ https://ncbi.nlm.nih.gov/pubmed/18579792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-09-115477 |
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