Stat5a serine 725 and 779 phosphorylation is a prerequisite for hematopoietic transformation

Stat5 transcription factors are essential gene regulators promoting proliferation, survival, and differentiation of all hematopoietic cell types. Mutations or fusions of oncogenic tyrosine kinases often result in constitutive Stat5 activation. We have modeled persistent Stat5 activity by using an on...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Friedbichler, Katrin, Kerenyi, Marc A., Kovacic, Boris, Li, Geqiang, Hoelbl, Andrea, Yahiaoui, Saliha, Sexl, Veronika, Müllner, Ernst W., Fajmann, Sabine, Cerny-Reiterer, Sabine, Valent, Peter, Beug, Hartmut, Gouilleux, Fabrice, Bunting, Kevin D., Moriggl, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938843/
https://ncbi.nlm.nih.gov/pubmed/20508164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-12-258913
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados