Activated STAT5 proteins induce activation of the PI 3-kinase/Akt and Ras/MAPK pathways via the Gab2 scaffolding adapter

The active forms of STAT5A (signal transducer and activator of transcription 5A) and STAT5B are able to relieve the cytokine dependence of haematopoietic cells and to induce leukaemia in mice. We have demonstrated previously that activation of the PI3K (phosphoinositide 3-kinase) signalling cascade...

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Detalhes bibliográficos
Main Authors: Nyga, Rémy, Pecquet, Christian, Harir, Noria, Gu, Haihua, Dhennin-Duthille, Isabelle, Régnier, Aline, Gouilleux-Gruart, Valérie, Lassoued, Kaïss, Gouilleux, Fabrice
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1188271/
https://ncbi.nlm.nih.gov/pubmed/15833084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041523
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