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STAT3 transcription factor is constitutively activated and is oncogenic in nasal-type NK/T-cell lymphoma

Nasal-type natural killer (NK) cell lymphoma is an infrequent aggressive malignant disease with very poor prognosis. We aimed to explore the possible role of the transcription factor STAT3 in the pathophysiology of this malignancy, as it was involved in oncogenesis and chemoresistance. For this, we...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Coppo, Paul, Gouilleux-Gruart, Valérie, Huang, Yenlin, Bouhlal, Hicham, Bouamar, Hakim, Bouchet, Sandrine, Perrot, Christine, Vieillard, Vincent, Dartigues, Peggy, Gaulard, Philippe, Agbalika, Félix, Douay, Luc, Lassoued, Kaiss, Gorin, Norbert-Claude
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group, Specialist Journals 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796333/
https://ncbi.nlm.nih.gov/pubmed/19421230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2009.91
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