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STAT3 transcription factor is constitutively activated and is oncogenic in nasal-type NK/T-cell lymphoma

Nasal-type natural killer (NK) cell lymphoma is an infrequent aggressive malignant disease with very poor prognosis. We aimed to explore the possible role of the transcription factor STAT3 in the pathophysiology of this malignancy, as it was involved in oncogenesis and chemoresistance. For this, we...

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Detalhes bibliográficos
Main Authors: Coppo, Paul, Gouilleux-Gruart, Valérie, Huang, Yenlin, Bouhlal, Hicham, Bouamar, Hakim, Bouchet, Sandrine, Perrot, Christine, Vieillard, Vincent, Dartigues, Peggy, Gaulard, Philippe, Agbalika, Félix, Douay, Luc, Lassoued, Kaiss, Gorin, Norbert-Claude
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group, Specialist Journals 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796333/
https://ncbi.nlm.nih.gov/pubmed/19421230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2009.91
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