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An intronic microRNA silences genes that are functionally antagonistic to its host gene
MicroRNAs (miRNAs) are short noncoding RNAs that down-regulate gene expression by silencing specific target mRNAs. While many miRNAs are transcribed from their own genes, nearly half map within introns of ‘host’ genes, the significance of which remains unclear. We report that transcriptional activat...
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| Главный автор: | |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2532712/ https://ncbi.nlm.nih.gov/pubmed/18684991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn513 |
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