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An intronic microRNA silences genes that are functionally antagonistic to its host gene

MicroRNAs (miRNAs) are short noncoding RNAs that down-regulate gene expression by silencing specific target mRNAs. While many miRNAs are transcribed from their own genes, nearly half map within introns of ‘host’ genes, the significance of which remains unclear. We report that transcriptional activat...

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Detalhes bibliográficos
Autor principal: Barik, Sailen
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532712/
https://ncbi.nlm.nih.gov/pubmed/18684991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn513
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