The open structure of a multi drug resistant HIV-1 protease is stabilized by crystal packing contacts

Antzeko izenburuak

• HIV-1 protease flaps spontaneously open and reclose in molecular dynamics simulations
  nork: Hornak, Viktor, et al.
  Argitaratua: (2006)
• Targeting structural flexibility in HIV-1 protease inhibitor binding
  nork: Hornak, Viktor, et al.
  Argitaratua: (2006)
• HIV-1 protease flaps spontaneously close to the correct structure in simulations following manual placement of an inhibitor into the open state
  nork: Hornak, Viktor, et al.
  Argitaratua: (2006)
• Solution Structure of HIV-1 Protease Flaps Probed by Comparison of Molecular Dynamics Simulation Ensembles and EPR Experiments
  nork: Ding, Fangyu, et al.
  Argitaratua: (2008)
• Accessory Mutations Maintain Stability in Drug Resistant HIV-1 Protease
  nork: Chang, Max W., et al.
  Argitaratua: (2011)