Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins.

Scrapie and Creutzfeldt-Jakob disease are transmissible, degenerative neurological diseases caused by prions. Considerable evidence argues that prions contain protease-resistant sialoglycoproteins, designated PrPSc, encoded by a cellular gene. The prion protein (PrP) gene also encodes a normal cellu...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Butler, D A, Scott, M R, Bockman, J M, Borchelt, D R, Taraboulos, A, Hsiao, K K, Kingsbury, D T, Prusiner, S B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253182/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3282080/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.5.1558-1564.1988
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