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Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins.

Scrapie and Creutzfeldt-Jakob disease are transmissible, degenerative neurological diseases caused by prions. Considerable evidence argues that prions contain protease-resistant sialoglycoproteins, designated PrPSc, encoded by a cellular gene. The prion protein (PrP) gene also encodes a normal cellu...

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Bibliografiske detaljer
Main Authors: Butler, D A, Scott, M R, Bockman, J M, Borchelt, D R, Taraboulos, A, Hsiao, K K, Kingsbury, D T, Prusiner, S B
Format: Artigo
Sprog:Inglês
Udgivet: 1988
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC253182/
https://ncbi.nlm.nih.gov/pubmed/3282080
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