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Synthesis of a Novel Dicyano Abietane Analogue—a Potential Anti-inflammatory Agent

From a structure–activity relationship perspective, the new abietane 5 having cyano groups at C-2 and C-13 and a phenolic ring C has been synthesized and evaluated biologically because the related compound 4 has high potency in inflammation models in vitro and in vivo. Compound 5 was synthesized fro...

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Detalhes bibliográficos
Main Authors: Honda, Tadashi, Yoshizawa, Hidenori, Sundararajan, Chitra, Gribble, Gordon W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2531246/
https://ncbi.nlm.nih.gov/pubmed/16599639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo060059+
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