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Asymmetric Synthesis of Polyfunctionalized Pyrrolidines from Sulfinimine-Derived Pyrrolidine 2-Phosphonates. Synthesis of Pyrrolidine 225C

[Image: see text] The Horner-Wadsworth-Emmons reaction of aldehydes with sulfinimine-derived 3-oxo pyrrolidine phosphonates represents a new method for the asymmetric synthesis of ring-functionalized cis-2,5-disubstituted 3-oxo pyrrolidines.

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Autors principals: Davis, Franklin A., Xu, He, Wu, Yongzhong, Zhang, Junyi
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2530903/
https://ncbi.nlm.nih.gov/pubmed/16706504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol060521c
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